New Year’s Eve and New Year’s Day are all about celebrating (or forgetting) the year just gone, and looking ahead to becoming a better/healthier/more successful you in 2025. And there’s no easier way to stick to your New Year’s resolution than a strange substance that causes a younger you to peel out from under your skin. Starring Demi Moore and Margaret Qualley, Coralie Fargeat’s The Substance is arguably the horror hit of the year. The film follows Elisabeth Sparkle (Moore), who takes the mysterious “substance” to keep her showbiz career alive.